Cathelicidin Mediates a Protective Role of Vitamin D in Ulcerative Colitis and Human Colonic Epithelial Cells

BACKGROUND: Vitamin D plays a protective role in ulcerative colitis (UC) patients through unclear mechanisms. Cathelicidin is an antimicrobial peptide induced by 1,25(OH)D2. Our goal was to evaluate the link between cathelicidin and vitamin D–associated clinical outcomes in UC patients, explore vita...

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Vydáno v:Inflamm Bowel Dis
Hlavní autoři: Gubatan, John, Mehigan, Gillian A, Villegas, Fernando, Mitsuhashi, Shuji, Longhi, Maria Serena, Malvar, Grace, Csizmadia, Eva, Robson, Simon, Moss, Alan C
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Basic Science Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216768/
https://ncbi.nlm.nih.gov/pubmed/31955203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izz330
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