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Reduced complement of dopaminergic neurons in the substantia nigra pars compacta of mice with a constitutive “low footprint” genetic knockout of alpha-synuclein

Previous studies of the alpha-synuclein null mutant mice on the C57Bl6 genetic background have revealed reduced number of dopaminergic neurons in their substantia nigra pars compacta (SNpc). However, the presence in genomes of the studied mouse lines of additional genetic modifications that affect e...

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Pubblicato in:Mol Brain
Autori principali: Goloborshcheva, Valeria V., Chaprov, Kirill D., Teterina, Ekaterina V., Ovchinnikov, Ruslan, Buchman, Vladimir L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216632/
https://ncbi.nlm.nih.gov/pubmed/32393371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00613-5
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