Effectiveness of Olaparib Treatment in a Patient with Gallbladder Cancer with an ATM‐Inactivating Mutation

Here, we report a case of postoperative recurrence of gallbladder carcinoma (GBC) in a patient who declined systemic chemotherapy. ATM S1905Ifs*25 and STK11 K262Sfs*25 mutations were detected by next‐generation sequencing. Oral administration of olaparib was initiated. One month later, the patient e...

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Dades bibliogràfiques
Publicat a:Oncologist
Autors principals: Zhang, Wei, Shi, Junping, Li, Rentao, Han, Zhiqiang, Li, Ling, Li, Guanghao, Yang, Bo, Yin, Qiang, Wang, Yingying, Ke, Yan, Li, Qiang
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2020
Matèries:
Precision Medicine Clinic: Molecular Tumor Board
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216437/
https://ncbi.nlm.nih.gov/pubmed/32045060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0498
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