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Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Bioactive Aflibercept In Vitro

PURPOSE: Current standard of care for neovascular eye diseases require repeated intravitreal bolus injections of anti-vascular endothelial growth factors (anti-VEGFs). The purpose of this study was to validate a degradable microsphere-thermoresponsive hydrogel drug delivery system (DDS) capable of r...

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Publicat a:Curr Eye Res
Autors principals: Liu, Wenqiang, Lee, Bao-Shiang, Mieler, William F., Kang-Mieler, Jennifer J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216294/
https://ncbi.nlm.nih.gov/pubmed/30295090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02713683.2018.1533983
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