Amino Acid Deletions in p6(Gag) Domain of HIV-1 CRF07_BC Ameliorate Galectin-3 Mediated Enhancement in Viral Budding

HIV-1 CRF07_BC is a recombinant virus with amino acid (a.a.) deletions in p6(Gag), which are overlapped with the Alix-binding domain. Galectin-3 (Gal3), a β-galactose binding lectin, has been reported to interact with Alix and regulate HIV-1 subtype B budding. This study aims to evaluate the role of...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Wang, Wen-Hung, Yeh, Chun-Sheng, Lin, Chih-Yen, Yuan, Ruei-Yu, Urbina, Aspiro Nayim, Lu, Po-Liang, Chen, Yen-Hsu, Chen, Yi-Ming Arthur, Liu, Fu-Tong, Wang, Sheng-Fan
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216183/
https://ncbi.nlm.nih.gov/pubmed/32326345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082910
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