Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells’ Motility and Focal Adhesion Formation

Non-muscle actins have been studied for many decades; however, the reason for the existence of both isoforms is still unclear. Here we show, for the first time, a successful inactivation of the ACTB (CRISPR clones with inactivated ACTB, CR-ACTB) and ACTG1 (CRISPR clones with inactivated ACTG1, CR-AC...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Malek, Natalia, Mrówczyńska, Ewa, Michrowska, Aleksandra, Mazurkiewicz, Ewa, Pavlyk, Iuliia, Mazur, Antonina Joanna
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216121/
https://ncbi.nlm.nih.gov/pubmed/32326615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082746
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares