Correlation of RAS-Pathway Mutations and Spontaneous Myeloid Colony Growth with Progression and Transformation in Chronic Myelomonocytic Leukemia—A Retrospective Analysis in 337 Patients

Although the RAS-pathway has been implicated as an important driver in the pathogenesis of chronic myelomonocytic leukemia (CMML) a comprehensive study including molecular and functional analyses in patients with progression and transformation has not been performed. A close correlation between RASo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Geissler, Klaus, Jäger, Eva, Barna, Agnes, Gurbisz, Michael, Graf, Temeida, Graf, Elmir, Nösslinger, Thomas, Pfeilstöcker, Michael, Tüchler, Heinz, Sliwa, Thamer, Keil, Felix, Geissler, Christoph, Heibl, Sonja, Thaler, Josef, Machherndl-Spandl, Sigrid, Zach, Otto, Weltermann, Ansgar, Bettelheim, Peter, Stauder, Reinhard, Zebisch, Armin, Sill, Heinz, Schwarzinger, Ilse, Schneeweiss, Bruno, Öhler, Leopold, Ulsperger, Ernst, Kusec, Rajko, Germing, Ulrich, Sperr, Wolfgang R., Knöbl, Paul, Jäger, Ulrich, Hörmann, Gregor, Valent, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215883/
https://ncbi.nlm.nih.gov/pubmed/32344757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21083025
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