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ABC Efflux Transporters and the Circuitry of miRNAs: Kinetics of Expression in Cancer Drug Resistance

Cancer drug resistance (CDR) is a major problem in therapeutic failure. Over 90% of patients with metastatic cancer present CDR. Several mechanisms underlie CDR, including the increased expression of efflux ABC transporters and epigenetic phenomena. Nevertheless, a topic that is not usually addresse...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gomes, Bruno C., Honrado, Mónica, Armada, Ana, Viveiros, Miguel, Rueff, José, Rodrigues, António S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215654/
https://ncbi.nlm.nih.gov/pubmed/32340269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082985
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