Autocrine Bradykinin Release Promotes Ischemic Preconditioning-Induced Cytoprotection in Bovine Aortic Endothelial Cells

The aims of this study were to assess whether ischemic preconditioning (PC) induces bradykinin (Bk) synthesis in bovine aortic endothelial cells (bAECs) and, if so, to explore the molecular mechanisms by which this peptide provides cytoprotection against hypoxia. PC was induced by exposing bAECs to...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Bellis, Alessandro, Sorriento, Daniela, Fiordelisi, Antonella, Izzo, Raffaele, Sadoshima, Junichi, Mauro, Ciro, Cerasuolo, Federica, Mancusi, Costantino, Barbato, Emanuele, Pilato, Emanuele, Trimarco, Bruno, Morisco, Carmine
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215376/
https://ncbi.nlm.nih.gov/pubmed/32340102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082965
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