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Molecular Insights Into the Causes of Human Thymic Hypoplasia With Animal Models

22q11.2 deletion syndrome (DiGeorge), CHARGE syndrome, Nude/SCID and otofaciocervical syndrome type 2 (OTFCS2) are distinct clinical conditions in humans that can result in hypoplasia and occasionally, aplasia of the thymus. Thymic hypoplasia/aplasia is first suggested by absence or significantly re...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bhalla, Pratibha, Wysocki, Christian A., van Oers, Nicolai S. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214791/
https://ncbi.nlm.nih.gov/pubmed/32431714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00830
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