Serious Hemorrhagic Complications After Successful Treatment of Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy With Defibrotide in Pediatric Patient With Myelodysplastic Syndrome

Background: Transplant-associated thrombotic microangiopathy (TAM) is a life-threatening complication of hematopoietic stem cell transplantation (HSCT). There is some evidence of endothelial injury playing a significant role in TAM development. The efficacy of defibrotide was demonstrated for prophy...

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Bibliographic Details
Published in:Front Pediatr
Main Authors: Laberko, Alexandra, Aksenova, Marina, Shipitsina, Irina, Khamin, Igor, Shcherbina, Anna, Balashov, Dmitry, Maschan, Alexei
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Pediatrics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214790/
https://ncbi.nlm.nih.gov/pubmed/32432059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2020.00155
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