Stimulation of L‐type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells

Making high‐quality dopamine (DA)‐producing cells for basic biological or small molecule screening studies is critical for the development of novel therapeutics for disorders of the ventral midbrain. Currently, many ventral midbrain assays have low signal‐to‐noise ratio due to low levels of cellular...

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Publicat a:Stem Cells Transl Med
Autors principals: Jefri, Malvin, Bell, Scott, Peng, Huashan, Hettige, Nuwan, Maussion, Gilles, Soubannier, Vincent, Wu, Hanrong, Silveira, Heika, Theroux, Jean‐Francois, Moquin, Luc, Zhang, Xin, Aouabed, Zahia, Krishnan, Jeyashree, O'Leary, Liam A., Antonyan, Lilit, Zhang, Ying, McCarty, Vincent, Mechawar, Naguib, Gratton, Alain, Schuppert, Andreas, Durcan, Thomas M., Fon, Edward A., Ernst, Carl
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2020
Matèries:
Pluripotent Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214648/
https://ncbi.nlm.nih.gov/pubmed/32154672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.18-0180
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