Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers

Fasting-mimicking diets delay tumor progression and sensitize a wide range of tumors to chemotherapy, but their therapeutic potential in combination with non-cytotoxic compounds is poorly understood. Here we show that vitamin C anticancer activity is limited by the up-regulation of the stress-induci...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Di Tano, Maira, Raucci, Franca, Vernieri, Claudio, Caffa, Irene, Buono, Roberta, Fanti, Maura, Brandhorst, Sebastian, Curigliano, Giuseppe, Nencioni, Alessio, de Braud, Filippo, Longo, Valter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214421/
https://ncbi.nlm.nih.gov/pubmed/32393788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16243-3
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