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Functional culture and in vitro genetic and small-molecule manipulation of adult mouse cardiomyocytes

Primary adult cardiomyocyte (aCM) represent the mature form of myocytes found in the adult heart. However, culture of aCMs in particular is challenged by poor survival and loss of phenotype, rendering extended in vitro experiments unfeasible. Here, we establish murine aCM culture methods that enhanc...

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發表在:Commun Biol
Main Authors: Callaghan, Neal I., Lee, Shin-Haw, Hadipour-Lakmehsari, Sina, Lee, Xavier A., Ahsan Siraj, M., Driouchi, Amine, Yip, Christopher M., Husain, Mansoor, Simmons, Craig A., Gramolini, Anthony O.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214405/
https://ncbi.nlm.nih.gov/pubmed/32393743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0946-9
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