Blockade of thymic stromal lymphopoietin and CRTH2 attenuates airway inflammation in a murine model of allergic asthma

BACKGROUND/AIMS: Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine that plays a key role in Th2-mediated inflammation, both directly by promoting the proliferation of naïve CD4 Th2 cells, and indirectly by activating dendritic cells (DCs). TSLP-activated DCs induce the expan...

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Vydáno v:Korean J Intern Med
Hlavní autoři: Lee, Hea Yon, Lee, Hwa Young, Hur, Jung, Kang, Hye Seon, Choi, Joon Young, Rhee, Chin Kook, Kang, Ji Young, Kim, Young Kyoon, Lee, Sook Young
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Association of Internal Medicine 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214371/
https://ncbi.nlm.nih.gov/pubmed/32183504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.2018.248
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