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Utilization of Physiologically Based Pharmacokinetic Modeling in Clinical Pharmacology and Therapeutics: an Overview

The purpose of this review was to assess the advancement of applications for physiologically based pharmacokinetic (PBPK) modeling in various therapeutic areas. We conducted a PubMed search, and 166 articles published between 2012 and 2018 on FDA-approved drug products were selected for further revi...

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Detalhes bibliográficos
Publicado no:Curr Pharmacol Rep
Main Authors: Perry, Courtney, Davis, Grace, Conner, Todd M., Zhang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214223/
https://ncbi.nlm.nih.gov/pubmed/32399388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40495-020-00212-x
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