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HOTAIR/miR‐125 axis‐mediated Hexokinase 2 expression promotes chemoresistance in human glioblastoma

Drug resistance is one of the major obstacles in glioblastoma (GBM) treatments using temozolomide (TMZ) based conventional chemotherapy. Recent studies revealed that Hexokinase 2 (HK2)‐mediated glycolysis is one of the sources, as the association of chemoresistance and the expression of HK2 was conf...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhang, Jinnan, Chen, Guangyong, Gao, Yufei, Liang, Huaxin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214183/
https://ncbi.nlm.nih.gov/pubmed/32279420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15233
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