Immune imbalance and activation are associated with lower lung function in youth with perinatally-acquired HIV

High CD8 T-cells and low CD4/CD8 are associated with lower lung function among youth living with perinatally-acquired HIV, despite antiretroviral therapy and CD4 preservation/reconstitution. Understanding these underlying mechanisms is critical to mitigate lung function impairment.

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Dettagli Bibliografici
Pubblicato in:J Allergy Clin Immunol
Autori principali: ATTIA, Engi F., JACOBSON, Denise, YU, Wendy, CROWELL, Claudia S., MALECHE-OBIMBO, Elizabeth, WILLIAMS, Paige L., WEST, T. Eoin, BURCHETT, Sandra K., KATTAN, Meyer, COLIN, Andrew A., ESKANDER, Sherry, CHUNG, Michael H., CROTHERS, Kristina, SHEARER, William T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214131/
https://ncbi.nlm.nih.gov/pubmed/31874184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.12.890
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