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Statistical significance of cluster membership for unsupervised evaluation of cell identities

MOTIVATION: Single-cell RNA-sequencing (scRNA-seq) allows us to dissect transcriptional heterogeneity arising from cellular types, spatio-temporal contexts and environmental stimuli. Transcriptional heterogeneity may reflect phenotypes and molecular signatures that are often unmeasured or unknown a...

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Publicat a:Bioinformatics
Autor principal: Chung, Neo Christopher
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214036/
https://ncbi.nlm.nih.gov/pubmed/32142108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa087
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