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G4Killer web application: a tool to design G-quadruplex mutations

MOTIVATION: G-quadruplexes (G4) are important regulatory non-B DNA structures with therapeutic potential. A tool for rational design of mutations leading to decreased propensity for G4 formation should be useful in studying G4 functions. Although tools exist for G4 prediction, no easily accessible t...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Brazda, Vaclav, Kolomaznik, Jan, Mergny, Jean-Louis, Stastny, Jiri
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214026/
https://ncbi.nlm.nih.gov/pubmed/31985802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa057
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