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InterLig: improved ligand-based virtual screening using topologically independent structural alignments

MOTIVATION: In the past few years, drug discovery processes have been relying more and more on computational methods to sift out the most promising molecules before time and resources are spent to test them in experimental settings. Whenever the protein target of a given disease is not known, it bec...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Mirabello, Claudio, Wallner, Björn
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214017/
https://ncbi.nlm.nih.gov/pubmed/32049311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa089
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