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Developmental loss of MeCP2 from VIP interneurons impairs cortical function and behavior

Rett Syndrome is a devastating neurodevelopmental disorder resulting from mutations in the gene MECP2. Mutations of Mecp2 that are restricted to GABAergic cell types largely replicate the behavioral phenotypes associated with mouse models of Rett Syndrome, suggesting a pathophysiological role for in...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Mossner, James M, Batista-Brito, Renata, Pant, Rima, Cardin, Jessica A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213975/
https://ncbi.nlm.nih.gov/pubmed/32343226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55639
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