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Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome
COVID-19 patients can present with pulmonary edema early in disease. We propose that this is due to a local vascular problem because of activation of bradykinin 1 receptor (B1R) and B2R on endothelial cells in the lungs. SARS-CoV-2 enters the cell via ACE2 that next to its role in RAAS is needed to...
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| Izdano u: | eLife |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7213974/ https://ncbi.nlm.nih.gov/pubmed/32338605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57555 |
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