Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis

Systemic juvenile idiopathic arthritis (sJIA) begins with fever, rash, and high-grade systemic inflammation but commonly progresses to a persistent afebrile arthritis. The basis for this transition is unknown. To evaluate a role for lymphocyte polarization, we characterized T cells from patients wit...

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Publicat a:JCI Insight
Autors principals: Henderson, Lauren A., Hoyt, Kacie J., Lee, Pui Y., Rao, Deepak A., Jonsson, A. Helena, Nguyen, Jennifer P., Rutherford, Kayleigh, Julé, Amélie M., Charbonnier, Louis-Marie, Case, Siobhan, Chang, Margaret H., Cohen, Ezra M., Dedeoglu, Fatma, Fuhlbrigge, Robert C., Halyabar, Olha, Hazen, Melissa M., Janssen, Erin, Kim, Susan, Lo, Jeffrey, Lo, Mindy S., Meidan, Esra, Son, Mary Beth F., Sundel, Robert P., Stoll, Matthew L., Nusbaum, Chad, Lederer, James A., Chatila, Talal A., Nigrovic, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213804/
https://ncbi.nlm.nih.gov/pubmed/32213704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.132508
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