Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis

Systemic juvenile idiopathic arthritis (sJIA) begins with fever, rash, and high-grade systemic inflammation but commonly progresses to a persistent afebrile arthritis. The basis for this transition is unknown. To evaluate a role for lymphocyte polarization, we characterized T cells from patients wit...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Henderson, Lauren A., Hoyt, Kacie J., Lee, Pui Y., Rao, Deepak A., Jonsson, A. Helena, Nguyen, Jennifer P., Rutherford, Kayleigh, Julé, Amélie M., Charbonnier, Louis-Marie, Case, Siobhan, Chang, Margaret H., Cohen, Ezra M., Dedeoglu, Fatma, Fuhlbrigge, Robert C., Halyabar, Olha, Hazen, Melissa M., Janssen, Erin, Kim, Susan, Lo, Jeffrey, Lo, Mindy S., Meidan, Esra, Son, Mary Beth F., Sundel, Robert P., Stoll, Matthew L., Nusbaum, Chad, Lederer, James A., Chatila, Talal A., Nigrovic, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213804/
https://ncbi.nlm.nih.gov/pubmed/32213704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.132508
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