Growth and differentiation factor 15 is secreted by skeletal muscle during exercise and promotes lipolysis in humans

We hypothesized that skeletal muscle contraction produces a cellular stress signal, triggering adipose tissue lipolysis to sustain fuel availability during exercise. The present study aimed at identifying exercise-regulated myokines, also known as exerkines, able to promote lipolysis. Human primary...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Laurens, Claire, Parmar, Anisha, Murphy, Enda, Carper, Deborah, Lair, Benjamin, Maes, Pauline, Vion, Julie, Boulet, Nathalie, Fontaine, Coralie, Marquès, Marie, Larrouy, Dominique, Harant, Isabelle, Thalamas, Claire, Montastier, Emilie, Caspar-Bauguil, Sylvie, Bourlier, Virginie, Tavernier, Geneviève, Grolleau, Jean-Louis, Bouloumié, Anne, Langin, Dominique, Viguerie, Nathalie, Bertile, Fabrice, Blanc, Stéphane, de Glisezinski, Isabelle, O’Gorman, Donal, Moro, Cedric
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213799/
https://ncbi.nlm.nih.gov/pubmed/32106110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131870
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