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Cell-associated HIV-1 RNA predicts viral rebound and disease progression after discontinuation of temporary early ART

Plasma viral load (VL) and CD4(+) T cell count are widely used as biomarkers of HIV type 1 (HIV-1) replication, pathogenesis, and response to antiretroviral therapy (ART). However, the clinical potential of cell-associated (CA) HIV-1 molecular markers is much less understood. Here, we measured CA HI...

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Publicado en:JCI Insight
Autores principales: Pasternak, Alexander O., Grijsen, Marlous L., Wit, Ferdinand W., Bakker, Margreet, Jurriaans, Suzanne, Prins, Jan M., Berkhout, Ben
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213790/
https://ncbi.nlm.nih.gov/pubmed/32097124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134196
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