Genetic algorithm-based personalized models of human cardiac action potential

We present a novel modification of genetic algorithm (GA) which determines personalized parameters of cardiomyocyte electrophysiology model based on set of experimental human action potential (AP) recorded at different heart rates. In order to find the steady state solution, the optimized algorithm...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Smirnov, Dmitrii, Pikunov, Andrey, Syunyaev, Roman, Deviatiiarov, Ruslan, Gusev, Oleg, Aras, Kedar, Gams, Anna, Koppel, Aaron, Efimov, Igor R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213718/
https://ncbi.nlm.nih.gov/pubmed/32392258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231695
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