ACT-01 THE SECOND GENERATION ANAPLASTIC LYMPHOMA KINASE (ALK) INHIBITOR CERITINIB EFFECTIVELY INDUCES CELL DEATH IN HUMAN GLIOBLASTOMA CELLS

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase which expresses only in the developmental stage of the brain during embryogenesis of human. On the other hand, a variety of ALK gene alterations, such as oncogenic fusion, activating point mutation, or wild type gene amplification, have...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Kawauchi, Daisuke, Takahashi, Masamichi, Yamamuro, Shun, Kobayashi, Tatsuya, Uchida, Eita, Iwadate, Yasuo, Ichimura, Koichi, Tomiyama, Arata
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213398/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz039.057
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