LPTO-08. INTRATHECAL TRASTUZUMAB PLUS/MINUS IT TOPOTECAN FOR PATIENTS WITH HER2+ BREAST CANCER AND LEPTOMENINGEAL METASTASIS

BACKGROUND: Leptomeningeal metastasis (LM) is an aggressive complication of cancer. No standard therapies exist, although at our institution we commonly use IT topotecan in good-risk patients. We report our experience in patients with HER2+ breast cancer (BC) LM treated with intrathecal (IT) trastuz...

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Vydáno v:Neurooncol Adv
Hlavní autoři: Trevino, Christopher R, Murthy, Rashmi K, Raghavendra, Akshara Singareeka, Loghin, Monica, Seligman, Christa, Ferguson, Sherise, Kamiya-Matsuoka, Carlos, Harrison, Rebecca, Sinicrope, Kaylyn D, Valero, Vicente, Tummala, Sudhakar, Hess, Kenneth, Tripathy, Debu, de Groot, John, O’Brien, Barbara
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213336/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.031
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