TRLS-09. RTOG1119: PHASE II RANDOMIZED STUDY OF WHOLE BRAIN RADIOTHERAPY / STEREOTACTIC RADIOSURGERY IN COMBINATION WITH CONCURRENT LAPATINIB IN PATIENTS WITH BRAIN METASTASIS FROM HER2-POSITIVE BREAST CANCER

The addition of trastuzumab to cytotoxic chemotherapy has improved outcomes for patients with HER2 positive breast cancer. Increased survival coupled with limited blood-brain barrier (BBB) penetration of trastuzumab may contribute to the increased incidence of brain metastasis in these patients. Hal...

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Bibliografiske detaljer
Udgivet i:Neurooncol Adv
Main Authors: Kim, In Ah, Winter, Kathryn, Peereboom, David, Sperduto, Paul, De Los Santos, Jennifer, Ogunleye, Tomi, Boulter, Daniel, White, Julia, Mehta, Minesh
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213269/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.042
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