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The emerging roles of vacuolar-type ATPase-dependent Lysosomal acidification in neurodegenerative diseases

BACKGROUND: Lysosomes digest extracellular material from the endocytic pathway and intracellular material from the autophagic pathway. This process is performed by the resident hydrolytic enzymes activated by the highly acidic pH within the lysosomal lumen. Lysosome pH gradients are mainly maintaine...

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Vydáno v:Transl Neurodegener
Hlavní autoři: Song, Qiaoyun, Meng, Bo, Xu, Haidong, Mao, Zixu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212675/
https://ncbi.nlm.nih.gov/pubmed/32393395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-020-00196-0
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