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Roles of active-site residues in catalysis, substrate binding, cooperativity, and the reaction mechanism of the quinoprotein glycine oxidase

The quinoprotein glycine oxidase from the marine bacterium Pseudoalteromonas luteoviolacea (PlGoxA) uses a protein-derived cysteine tryptophylquinone (CTQ) cofactor to catalyze conversion of glycine to glyoxylate and ammonia. This homotetrameric enzyme exhibits strong cooperativity toward glycine bi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mamounis, Kyle J., Yukl, Erik T., Davidson, Victor L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212659/
https://ncbi.nlm.nih.gov/pubmed/32234764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013198
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