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The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress

Optic atrophy 1 (OPA1) is a dynamin protein that mediates mitochondrial fusion at the inner membrane. OPA1 is also necessary for maintaining the cristae and thus essential for supporting cellular energetics. OPA1 exists as membrane-anchored long form (L-OPA1) and short form (S-OPA1) that lacks the t...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Lee, Hakjoo, Smith, Sylvia B., Sheu, Shey-Shing, Yoon, Yisang
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212625/
https://ncbi.nlm.nih.gov/pubmed/32245890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010983
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