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A flexible network of vimentin intermediate filaments promotes migration of amoeboid cancer cells through confined environments

Tumor cells can spread to distant sites through their ability to switch between mesenchymal and amoeboid (bleb-based) migration. Because of this difference, inhibitors of metastasis must account for each migration mode. However, the role of vimentin in amoeboid migration has not been determined. Bec...

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Pubblicato in:J Biol Chem
Autori principali: Lavenus, Sandrine B., Tudor, Sara M., Ullo, Maria F., Vosatka, Karl W., Logue, Jeremy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212622/
https://ncbi.nlm.nih.gov/pubmed/32234762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011537
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