Different p53 genotypes regulating different phosphorylation sites and subcellular location of CDC25C associated with the formation of polyploid giant cancer cells

BACKGROUND: Our previous studies have confirmed that cobalt chloride (CoCl(2)) can induce the formation of polyploid giant cancer cells (PGCCs), which is the key to the heterogeneity of solid tumors. PGCC formation is closely related to the abnormal expression of cell cycle-related proteins and cell...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Liu, Kai, Zheng, Minying, Zhao, Qi, Zhang, Kexin, Li, Zugui, Fu, Fangmei, Zhang, Hao, Du, Jiaxing, Li, Yuwei, Zhang, Shiwu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212590/
https://ncbi.nlm.nih.gov/pubmed/32393310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01588-w
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