Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups

Because polygenic risk scores (PRSs) for coronary heart disease (CHD) are derived from mainly European ancestry (EA) cohorts, their validity in African ancestry (AA) and Hispanic ethnicity (HE) individuals is unclear. We investigated associations of “restricted” and genome-wide PRSs with CHD in thre...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Am J Hum Genet
Autores principales: Dikilitas, Ozan, Schaid, Daniel J., Kosel, Matthew L., Carroll, Robert J., Chute, Christopher G., Denny, Joshua A., Fedotov, Alex, Feng, QiPing, Hakonarson, Hakon, Jarvik, Gail P., Lee, Ming Ta Michael, Pacheco, Jennifer A., Rowley, Robb, Sleiman, Patrick M., Stein, C. Michael, Sturm, Amy C., Wei, Wei-Qi, Wiesner, Georgia L., Williams, Marc S., Zhang, Yanfei, Manolio, Teri A., Kullo, Iftikhar J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212267/
https://ncbi.nlm.nih.gov/pubmed/32386537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.04.002
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares