Statins and the COVID-19 main protease: in silico evidence on direct interaction

INTRODUCTION: No proven drug and no immunisation are yet available for COVID-19 disease. The SARS-CoV-2 main protease (Mpro), a key coronavirus enzyme, which is a potential drug target, has been successfully crystallised. There is evidence suggesting that statins exert anti-viral activity and may bl...

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Dettagli Bibliografici
Pubblicato in:Arch Med Sci
Autori principali: Reiner, Željko, Hatamipour, Mahdi, Banach, Maciej, Pirro, Matteo, Al-Rasadi, Khalid, Jamialahmadi, Tannaz, Radenkovic, Dina, Montecucco, Fabrizio, Sahebkar, Amirhossein
Natura: Artigo
Lingua:Inglês
Pubblicazione: Termedia Publishing House 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212226/
https://ncbi.nlm.nih.gov/pubmed/32399094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2020.94655
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