Excessive ADAM17 activation occurs in uremic patients and may contribute to their immunocompromised status

INTRODUCTION: We previously reported that fibroblast growth factor 23 (FGF23)‐klotho signaling plays a role in B cell immunity. Despite high serum levels of FGF23, a decline in immunity is frequently observed in patients on hemodialysis (HD); thus, abnormalities in the FGF23‐klotho signaling pathway...

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Bibliographische Detailangaben
Veröffentlicht in:Immun Inflamm Dis
Hauptverfasser: Yashiro, Mitsuru, Ohya, Masaki, Mima, Toru, Nakashima, Yuri, Kawakami, Kazuki, Sonou, Tomohiro, Tatsuta, Koichi, Yamano, Yukiko, Negi, Shigeo, Shigematsu, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212198/
https://ncbi.nlm.nih.gov/pubmed/32180373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.298
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