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Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis

The capacity of Mycobacterium tuberculosis (Mtb) to tolerate multiple antibiotics represents a major problem in tuberculosis (TB) management. Heterogeneity in Mtb populations is one of the factors that drives antibiotic tolerance during infection. However, the mechanisms underpinning this variation...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Mishra, Richa, Kohli, Sakshi, Malhotra, Nitish, Bandyopadhyay, Parijat, Mehta, Mansi, Munshi, MohamedHusen, Adiga, Vasista, Ahuja, Vijay Kamal, Shandil, Radha K., Rajmani, Raju S., Seshasayee, Aswin Sai Narain, Singh, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212044/
https://ncbi.nlm.nih.gov/pubmed/31723039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaw6635
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