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Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

Cellular starvation is typically a consequence of tissue injury that disrupts the local blood supply but can also occur where cell populations outgrow the local vasculature, as observed in solid tumors. Cells react to nutrient deprivation by adapting their metabolism, or, if starvation is prolonged,...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Püschel, Franziska, Favaro, Francesca, Redondo-Pedraza, Jaime, Lucendo, Estefanía, Iurlaro, Raffaella, Marchetti, Sandrine, Majem, Blanca, Eldering, Eric, Nadal, Ernest, Ricci, Jean-Ehrland, Chevet, Eric, Muñoz-Pinedo, Cristina
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211964/
https://ncbi.nlm.nih.gov/pubmed/32312819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913707117
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