Comprehensive characterisation of pancreatic ductal adenocarcinoma with microsatellite instability: histology, molecular pathology and clinical implications

OBJECTIVE: Recently, tumours with microsatellite instability (MSI)/defective DNA mismatch repair (dMMR) have gained considerable interest due to the success of immunotherapy in this molecular setting. Here, we aim to clarify clinical-pathological and/or molecular features of this tumour subgroup thr...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Luchini, Claudio, Brosens, Lodewijk A A, Wood, Laura D, Chatterjee, Deyali, Shin, Jae Il, Sciammarella, Concetta, Fiadone, Giulia, Malleo, Giuseppe, Salvia, Roberto, Kryklyva, Valentyna, Piredda, Maria L, Cheng, Liang, Lawlor, Rita T, Adsay, Volkan, Scarpa, Aldo
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Pancreas
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211065/
https://ncbi.nlm.nih.gov/pubmed/32350089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2020-320726
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