Par complex cluster formation mediated by phase separation

The evolutionarily conserved Par3/Par6/aPKC complex regulates the polarity establishment of diverse cell types and distinct polarity-driven functions. However, how the Par complex is concentrated beneath the membrane to initiate cell polarization remains unclear. Here we show that the Par complex ex...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Liu, Ziheng, Yang, Ying, Gu, Aihong, Xu, Jiawen, Mao, Ying, Lu, Haojie, Hu, Weiguo, Lei, Qun-Ying, Li, Zhouhua, Zhang, Mingjie, Cai, Yu, Wen, Wenyu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211019/
https://ncbi.nlm.nih.gov/pubmed/32385244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16135-6
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