Bifidobacteria shape host neural circuits during postnatal development by promoting synapse formation and microglial function

We hypothesized that early-life gut microbiota support the functional organization of neural circuitry in the brain via regulation of synaptic gene expression and modulation of microglial functionality. Germ-free mice were colonized as neonates with either a simplified human infant microbiota consor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Luck, Berkley, Engevik, Melinda A., Ganesh, Bhanu Priya, Lackey, Elizabeth P., Lin, Tao, Balderas, Miriam, Major, Angela, Runge, Jessica, Luna, Ruth Ann, Sillitoe, Roy V., Versalovic, James
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210968/
https://ncbi.nlm.nih.gov/pubmed/32385412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64173-3
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