CRISPR screening identifies M1AP as a new MYC regulator with a promoter-reporter system

BACKGROUND: MYC is one of the proto-oncogenes contributing to tumorigenesis in many human cancers. Although the mechanism of MYC regulation is still not fully understood, learning about the comprehensive mechanism controlling the transcriptional activity of MYC will lead to therapeutic targets. The...

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發表在:PeerJ
Main Authors: Yamamoto, Akiko, Kurata, Morito, Onishi, Iichiroh, Sugita, Keisuke, Matsumura, Miwa, Ishibashi, Sachiko, Ikeda, Masumi, Yamamoto, Kouhei, Kitagawa, Masanobu
格式: Artigo
語言:Inglês
出版: PeerJ Inc. 2020
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210806/
https://ncbi.nlm.nih.gov/pubmed/32411526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9046
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