IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors

Recently, cytoophidium, a nonmembrane-bound intracellular polymeric structure, has been shown to exist in various organisms, including tumor tissues, but its function and mechanism have not yet been examined. Examination of cytoophidia-assembled gene inosine monophosphate dehydrogenase (IMPDH) and c...

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Gepubliceerd in:Mol Ther
Hoofdauteurs: Ruan, Hailong, Song, Zhengshuai, Cao, Qi, Ni, Dong, Xu, Tianbo, Wang, Keshan, Bao, Lin, Tong, Junwei, Xiao, Haibing, Xiao, Wen, Cheng, Gong, Xiong, Zhiyong, Liang, Huageng, Liu, Di, Wang, Liang, Olivier, Tredan, Jane, Boyle Helen, Yang, Hongmei, Zhang, Xiaoping, Chen, Ke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2020
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210706/
https://ncbi.nlm.nih.gov/pubmed/32209435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.03.001
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