Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing

Manipulation of proteins by chemical modification is a powerful way to decipher their function. However, most ribosome-dependent and semi-synthetic methods have limitations in the number and type of modifications that can be introduced, especially in live cells. Here, we present an approach to incor...

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Publicado en:Nat Commun
Main Authors: Khoo, K. K., Galleano, I., Gasparri, F., Wieneke, R., Harms, H., Poulsen, M. H., Chua, H. C., Wulf, M., Tampé, R., Pless, S. A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210297/
https://ncbi.nlm.nih.gov/pubmed/32385250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16208-6
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