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SAT-293 Osteocalcin and Exercise Improve Mood and Cognition in Female Mice with High-Fat Diet Induced Type 2 Diabetes

The skeleton has been characterized as an endocrine organ, demonstrating a capacity to modulate cognition, mood and energy homeostasis (1,2). These endocrine actions of the skeleton have been attributed to the osteoblast-derived peptide osteocalcin. In mice, uncarboxylated osteocalcin (ucOCN) decrea...

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Pubblicato in:J Endocr Soc
Autori principali: Rentz, Jesse, Winberg, Jordan, Swardfager, Walter, Mitchell, Jane
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209751/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.500
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