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OR23-05 Human Absorption, Metabolism, Excretion, and Absolute Oral Bioavailability of (14)C-CRN00808, an Orally Bioavailable, Nonpeptide, Selective, Somatostatin Receptor 2 (sST2) Biased Agonist for the Treatment of Acromegaly

Injected depot formulations of somatostatin peptide analogs are routinely used to treat acromegaly and neuroendocrine tumors (NETs). CRN00808, a small molecule nonpeptide selective somatostatin receptor 2 (sst2) agonist, is being evaluated for efficacy and safety in patients with acromegaly. The cur...

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Bibliografiske detaljer
Udgivet i:J Endocr Soc
Main Authors: Madan, Ajay, Luo, Rosa, Cook, Stephen Ferrara, Struthers, Scott, van Marle, Sjoerd, Krasner, Alan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209640/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.696
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