OR07-04 A Novel Ex Vivo Live-Cell Interrogative Assay of Human Parathyroid Tissue Reveals Distinct Mechanisms of Calcium Sensing Failure in Primary, Secondary, and Tertiary Hyperparathyroidism

Disruption of calcium homeostasis is common to all forms of hyperparathyroidism (HPT), but the underlying biochemical mechanisms that distinguish the various forms of HPT pathology remain poorly characterized. We previously have observed that the kinetics and amplitude of CASR-mediated signaling var...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Zhang, Jie, Zhang, Run, Foft, Jessica, Starks, Catherine, Gosnell, Jessica Erin, Roman, Sanziana, Sosa, Julie Ann, Koh, James
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Bone and Mineral Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209402/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.526
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