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The double-edged sword role of fibroblasts in the interaction with cancer cells; an agent-based modeling approach

Fibroblasts as key components of tumor microenvironment show different features in the interaction with cancer cells. Although, Normal fibroblasts demonstrate anti-tumor effects, cancer associated fibroblasts are principal participant in tumor growth and invasion. The ambiguity of fibroblasts functi...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Heidary, Zarifeh, Ghaisari, Jafar, Moein, Shiva, Haghjooy Javanmard, Shaghayegh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209353/
https://ncbi.nlm.nih.gov/pubmed/32384110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232965
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